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KMID : 0363220070450111230
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Korean Journal of Dermatology
2007 Volume.45 No. 11 p.1230 ~ p.1232
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Treatment of Recalcitrant Acquired Reactive Perforating Collagenosis With Low-dose Allpurinol
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Shin Mi-Seon
Lee Doo-Rak
Park Mi-Youn
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Abstract
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Reactive perforating collagenosis is one of a range of essential perforating disorders and is characterized by the transepithelial elimination of altered collagen. Two types have been recognized: the inherited, or childhood form and the acquired, or adult form. Acquired reactive perforating collagenosis is associated with systemic diseases, especially diabetes mellitus and/or renal failure. We report that a low-dose allopurinol showed dramatic effects on acquired reactive perforating collagenosis, which was associated with hypothyroidism and chronic renal failure caused by diabetic nephropathy.
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KEYWORD
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Acquired reactive perforating collagenosis, Allpurinol
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